clang 11 throws an error when using undefined variables starting with
TARGET_OS_, and TARGET_OS_SIMULATOR is missing in earlier versions
of macOS, so the code would not compile without an additional guard.
See also ICU-13440.
/* Backup setting of ICU_DATA_DIR_PREFIX_ENV_VAR
(needed for some Darwin ICU build environments) */
-#if U_PLATFORM_IS_DARWIN_BASED && TARGET_OS_SIMULATOR
+#if U_PLATFORM_IS_DARWIN_BASED && defined(TARGET_OS_SIMULATOR) && TARGET_OS_SIMULATOR
# if !defined(ICU_DATA_DIR_PREFIX_ENV_VAR)
# define ICU_DATA_DIR_PREFIX_ENV_VAR "IPHONE_SIMULATOR_ROOT"
# endif