--with-pydebug is commonly used to find memory leaks.
But opcache makes it harder.
So disable opcache when Py_DEBUG is defined.
#endif
/* per opcode cache */
+#ifdef Py_DEBUG
+// --with-pydebug is used to find memory leak. opcache makes it harder.
+// So we disable opcache when Py_DEBUG is defined.
+// See bpo-37146
+#define OPCACHE_MIN_RUNS 0 /* disable opcache */
+#else
#define OPCACHE_MIN_RUNS 1024 /* create opcache when code executed this time */
+#endif
#define OPCACHE_STATS 0 /* Enable stats */
#if OPCACHE_STATS